bookmark_borderLong-COVID Update

by Daniel Brouse

COVID-19, caused by the SARS-CoV-2 virus, has left an indelible mark on global health, demonstrating not only its immediate threat but also the potential for enduring consequences. This article explores the profound and lasting impact of COVID-19, delving into the virus’s role in chronic conditions and its ability to leave a lasting imprint on various aspects of health.

Long-Term Complications and Excess Deaths

A COVID-19 infection often leads to persistent complications that significantly diminish both the quality of life and life expectancy. Shockingly, 10% of excess deaths can be directly attributed to COVID itself, while the remaining 90% are attributed to what can be considered COVID’s silent killers. Individuals who have experienced COVID may face a diminished quality of life and an increased risk of premature death. Dr. Rob Wust underscores this by stating, “There is something inside the body going wrong with the disease.”

Long-COVID: A Looming Reality

For those who have contracted COVID, the probability of developing chronic conditions, known as Long-COVID, is a staggering 99%. This alarming statistic underscores the pervasive and lasting impact of the virus on an individual’s health.

Key Insights into COVID-19’s Long-Term Effects

  1. Direct Impact on Organs:
    • COVID-19 has been responsible for millions of deaths and has caused long-term damage to vital organs, leaving many survivors permanently disabled.
  2. Persistent Viral Presence:
    • SARS-CoV-2 can persist in the body for months or even years, causing chronic infections and leaving behind viral proteins associated with Long-COVID. This persistence is comparable to other viruses like Chicken Pox leading to Shingles or Epstein-Barr virus contributing to Mononucleosis and Multiple Sclerosis.
  3. Compromised Immune System and Autoimmune Risks:
    • Post-COVID individuals often experience a compromised immune system and an increased risk of autoimmune diseases. Local immune responses may be disturbed by both mental and physical exertion in long-COVID patients.
  4. Genetic and Epigenetic Changes:
    • SARS-CoV-2 induces genetic and epigenetic alterations to DNA, resulting in a compromised immune system, elevated risks of diabetes, hypertension, cancer, and damage to neurological, circulatory, and cardiovascular systems. Predisposed conditions are likely to escalate to more advanced stages.
  5. Complexity of Long-COVID:
    • Long-COVID is likely a multifaceted condition involving persistent virus presence, residual viral proteins, and lasting epigenetic and genetic changes, potentially lasting indefinitely.
  6. Increased Risks with Reinfection:
    • Reinfection with COVID amplifies the risks of death, hospitalization, and multi-organ damage, exacerbating underlying conditions across various bodily systems.

Understanding the epigenetic changes induced by COVID, including the downregulation of NAD+ and the impact on tryptophan, sheds light on the physical and mental health challenges faced by individuals. The deficiency in niacin, zinc, and vitamin D is a common consequence. It is crucial to recognize that COVID’s epigenetic changes may vary widely based on an individual’s genetic makeup, requiring tailored treatments for optimal outcomes.

COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderCOVID-19 and Omicron Updates

2021/12/04
We’re starting to find out more about Omicron:
1)”Previous infection used to protect against Delta but now with Omicron that doesn’t seem to be the case,” said Anne von Gottberg, microbiologist at South Africa’s National Institute for Communicable Diseases.”
2) risk of breakthrough vaccination is also much higher. Out of 600 fully vaccinated travelers from South Africa, 61 tested positive for COVID. 16 of those were Omicron.
3) a much higher percentage of 20-30 years are being hospitalized
4) an alarming percentage of children under 2 are being hospitalized.
5) the Omicron variant has become dominant in South Africa. Cases of COVID have gone from 200/day, to 400, to 1,000 to 2,000, to 4,000, to 8,000, to over 11,000/day in as many days.
Remember, when you hear of cases being “mild”, that means mild for COVID (eg not hospitalized). All of the cases I’ve studied have been symptomatic individuals that are fully vaccinated.

Omicron Update December 9, 2021
Omicron Update:
* Pfizer says the booster offers protection
* Pfizer says 4th dose may be required
* South Africa says Pfizer offers 1/40th the protection as Delta
* Reinfection is 3 times more likely than with Delta
* South Africa cases are up 255% in a week
* 4x’s more transmissible than Delta
* UK cases could exceed 1 million by the end of this month
* typical seasonal viruses’ severity is up… suggesting recovery from COVID results in a compromised immune system. T cells may lose effectiveness against any pathogen

“In other words, Omicron is spreading in highly immune populations as quickly as the original virus did in populations with no immunity at all. If this holds and is left uncontrolled, a big Omicron wave lies ahead—bigger than we would have expected with Delta. Cases were already surging ahead of winter. The U.S. already had a too-low vaccination rate. And now Omicron threatens to eat away at the immunity we thought we had.”

Omicron and Other COVID Variants / the Long Term Pandemic

COVID and Cats: A scientist friend called me last night… wanted to make sure I stocked up on enough masks and supplies for the next round featuring Omicron. We got to talking about severity of variants and what the most likely scenarios are: 1) the virus stays for a prolonged period in an unvaccinated immune […]

bookmark_borderCISP (COVID-19 Induced Secondary Pellagra) Long Haulers Syndrome

COVID Long Haulers Syndrome is COVID Induced Secondary Pellagra (CISP).

By treating the population for pellagra:

  • new COVID cases can be prevented (prophylactic)
  • the severity and duration of COVID symptoms can be reduced (treatment)
  • COVID-long can be cured (cure)

THE PROTOCOL: Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium.

Dr. Ade Wentzel from Port Elizabeth (South Africa) and his colleagues, Robert Miller (Cape Town) and Guy Richards (Johannesburg), developed a diet based protocol based on their research COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity.

Long haulers syndrome is the depletion of NAD+ (nicotinamide adenine dinucleotide). NAD+ is involved in cell creation, maintenance, metabolism, and regulating cell processes. COVID both increases the breakdown of NAD+ and decreases the production of NAD+. The result is the same as the disease pellagra. A niacin deficiency results in pellagra. Long haulers syndrome is COVID-19 Induced Secondary Pellagra (CISP).

Index to COVID-19 / SARS-CoV-2 / Novel Coronavirus

COVID: The Cure?
Could Nicotinamide adenine dinucleotide (NAD+) be both a prophylactic and a treatment for COVID-19?

COVID-19: NAD+ Protocol
NAD+ is a crucial part of the immune system. COVID depletes your NAD+. The body needs the time and materials necessary to replenish NAD+.
Included in the elements you need are Vitamin B3,
Vitamin D, Vitamin C, Quercetin,
Zinc, and Selenium.

COVID-19: Immunity, Antibodies, and Memory T Cells
Until more is known, recovered COVID patients should take great care and avoid exposure to all bacteria and viruses, including COVID.

COVID-19 and Negative Feedback Loops
The more often your body suffers damage, than the more severe each additional exposure will become.

COVID, Tryptophan, Stress, Anxiety, and Pellagra
COVID depletes your NAD+. The body depletes tryptophan trying to make NAD+. This causes anxiety.

COVID, Vitamin K, and NAD+
… low NAD+ will result in low Vitamin K metabolism interfering with blood thinner medications and blood coagulation.

COVID Long Haulers Syndrome: NAD+ Deficiency
Research by Ade Wentzel, Robert Miller, and Guy Richards has found COVID-long (Long Haulers Syndrome) is a result of an NAD+ deficiency caused by SARS-CoV-2 (novel coronavirus).


COVID: Vitamin D, Sunlight, the Season, and People of Color

A human’s main source of Vitamin D is the synthesis of UVB radiation through your skin. The chemical reaction creates Vitamin D and other photoproducts essential for a healthy immune system. Taking a Vitamin D supplement is NOT the same as your body making Vitamin D.

COVID-19 Testimonial
There may be a complete recovery from COVID.

The Real Mortality Rate of COVID-19
The formula for calculating a mortality rate.

The Economic Costs of COVID Re-openings
What is the cost of a lifelong disability?

Difficulty of Testing for
COVID Infection and COVID Exposure

COVID-19 and Air Pollution
Large portions of world are susceptible to particulate and ozone pollution causing pre-existing respiratory and immune system problems.

bookmark_borderHow To Get Well

Don’t know what’s wrong and not sure where to turn for expert medical advice and treatment?

If you have a serious chronic condition, it may help you to know that it will take time to reverse a process that has developed over many years. There is no quick fix or magic bullet available for most chronic degenerative disorders. It takes a physician like Dr. Singer to apply good, scientific medical knowledge to help the healing process begin.

Maybe it’s time to visit Dr. Jonathan Singer, one of the pioneers in combining traditional medical care and natural treatments at his health care clinic in Denver, Colorado.

 
Dr. Jonathan Singer Understands When You Just Don’t Feel Well:
Visit Dr. Jonathan Singer’s Website

bookmark_borderSuperbug Medieval Remedy

Anglo-Saxon cow bile and garlic potion kills MRSA

In the UK, the Telegraph reports:

A thousand-year-old medieval remedy for eye infections which was discovered in a manuscript in the British Library has been found to kill the superbug MRSA.

Anglo-Saxon expert Dr Christina Lee, from the School of English, at Nottingham University, recreated the 10th century potion to see if it really worked as an antibacterial remedy.

The ‘eyesalve’ recipe calls for two species of Allium (garlic and onion or leek), wine and oxgall (bile from a cow’s stomach).

It describes a very specific method of making the topical solution including the use of a brass vessel to brew it, a strainer to purify it and an instruction to leave the mixture for nine days before use.

None of the experts really expected the concoction to work. But when it was tested, microbiologists were amazed to find that not only did the salve clear up styes, but it also tackled the deadly superbug MRSA, which is resistant to many antibiotics.

“We were genuinely astonished at the results of our experiments in the lab,” said Dr Lee.

“We believe modern research into disease can benefit from past responses and knowledge, which is largely contained in non-scientific writings.

“But the potential of these texts to contribute to addressing the challenges cannot be understood without the combined expertise of both the arts and science.”

Dr Lee translated the recipe from Bald’s Leechbook, a leatherbound Old Enlgish manuscript which is kept in the British Library.

The Leechbook is widely thought of as one of the earliest known medical textbooks and contains Anglo-Saxon medical advice and recipes for medicines, salves and treatments.

“Medieval leech books and herbaria contain many remedies designed to treat what are clearly bacterial infections, weeping wounds/sores, eye and throat infections, skin conditions such as erysipelas, leprosy and chest infections,” Dr Lee added.

The scientists at Nottingham made four separate batches of the remedy using fresh ingredients each time, as well as a control treatment using the same quantity of distilled water and brass sheeting to mimic the brewing container but without the vegetable compounds.

None of the individual ingredients alone had any measurable effect, but when combined according to the recipe the MRSA populations were almost totally obliterated: about one bacterial cell in a thousand survived in mice wounds.

Researchers believe the antibacterial effect of the recipe is not due to a single ingredient but the combination used and brewing methods. Further research is planned to investigate how and why this works.

Microbiologists at Nottingham University said they were ‘genuinely amazed’ by the discovery.

“We thought that Bald’s eyesalve might show a small amount of antibiotic activity, because each of the ingredients has been shown by other researchers to have some effect on bacteria in the lab,” said Dr Freya Harrison who led the work in the laboratory.

“But we were absolutely blown away by just how effective the combination of ingredients was.

“This truly cross-disciplinary project explores a new approach to modern health care problems by testing whether medieval remedies contain ingredients which kill bacteria or interfere with their ability to cause infection”.

Scientist Dr Steve Diggle added: “When we built this recipe in the lab I didn’t really expect it to actually do anything.

“When we found that it could actually disrupt and kill cells in (MRSA) biofilms, I was genuinely amazed.”

Dr Kendra Rumbaugh, of Texas Tech University in the US, who was asked to replicate the findings, said that the salve performed ‘good if not better’ than traditional antibiotics at tackling the superbug.

The team at Nottingham is seeking more funding to extend the research so that it could be tested on humans.

The findings were presented at the Annual Conference of the Society for General Microbiology in Birmingham which runs from March 30.