bookmark_borderLong-COVID Update

by Daniel Brouse

COVID-19, caused by the SARS-CoV-2 virus, has left an indelible mark on global health, demonstrating not only its immediate threat but also the potential for enduring consequences. This article explores the profound and lasting impact of COVID-19, delving into the virus’s role in chronic conditions and its ability to leave a lasting imprint on various aspects of health.

Long-Term Complications and Excess Deaths

A COVID-19 infection often leads to persistent complications that significantly diminish both the quality of life and life expectancy. Shockingly, 10% of excess deaths can be directly attributed to COVID itself, while the remaining 90% are attributed to what can be considered COVID’s silent killers. Individuals who have experienced COVID may face a diminished quality of life and an increased risk of premature death. Dr. Rob Wust underscores this by stating, “There is something inside the body going wrong with the disease.”

Long-COVID: A Looming Reality

For those who have contracted COVID, the probability of developing chronic conditions, known as Long-COVID, is a staggering 99%. This alarming statistic underscores the pervasive and lasting impact of the virus on an individual’s health.

Key Insights into COVID-19’s Long-Term Effects

  1. Direct Impact on Organs:
    • COVID-19 has been responsible for millions of deaths and has caused long-term damage to vital organs, leaving many survivors permanently disabled.
  2. Persistent Viral Presence:
    • SARS-CoV-2 can persist in the body for months or even years, causing chronic infections and leaving behind viral proteins associated with Long-COVID. This persistence is comparable to other viruses like Chicken Pox leading to Shingles or Epstein-Barr virus contributing to Mononucleosis and Multiple Sclerosis.
  3. Compromised Immune System and Autoimmune Risks:
    • Post-COVID individuals often experience a compromised immune system and an increased risk of autoimmune diseases. Local immune responses may be disturbed by both mental and physical exertion in long-COVID patients.
  4. Genetic and Epigenetic Changes:
    • SARS-CoV-2 induces genetic and epigenetic alterations to DNA, resulting in a compromised immune system, elevated risks of diabetes, hypertension, cancer, and damage to neurological, circulatory, and cardiovascular systems. Predisposed conditions are likely to escalate to more advanced stages.
  5. Complexity of Long-COVID:
    • Long-COVID is likely a multifaceted condition involving persistent virus presence, residual viral proteins, and lasting epigenetic and genetic changes, potentially lasting indefinitely.
  6. Increased Risks with Reinfection:
    • Reinfection with COVID amplifies the risks of death, hospitalization, and multi-organ damage, exacerbating underlying conditions across various bodily systems.

Understanding the epigenetic changes induced by COVID, including the downregulation of NAD+ and the impact on tryptophan, sheds light on the physical and mental health challenges faced by individuals. The deficiency in niacin, zinc, and vitamin D is a common consequence. It is crucial to recognize that COVID’s epigenetic changes may vary widely based on an individual’s genetic makeup, requiring tailored treatments for optimal outcomes.

COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderAir Pollution Cause of Cognitive Decline and Dementia

In a UK study, a causal relationship has been established between air pollution and cognitive decline / dementia. The primary cause is a decline in blood flow to the brain.

Cognitive decline, dementia and air pollution

COMEAP reviewed nearly 70 studies in human populations (epidemiological studies) which looked at possible links between air pollution and a decline in mental ability and dementia in older people. They also considered studies which investigated how air pollution might affect the brain.

From this review, it can be concluded that it is likely that air pollution does contribute to these effects. The most likely way this occurs is through effects on the circulation. It is known that air pollutants, particularly small particles, can affect the heart and blood vessels, including to the brain.

WORST CITIES FOR OZONE POLLUTION
#1: Los Angeles-Long Beach, CA
#2: Bakersfield, CA
#3: Visalia, CA
#4: Fresno-Madera-Hanford, CA
#5: Phoenix-Mesa, AZ
#6: San Diego-Chula Vista-Carlsbad, CA
#7: Denver-Aurora, CO
#8: Houston-The Woodlands, TX
#9: Sacramento-Roseville, CA
#10: Salt Lake City-Provo-Orem, UT
#11: Las Vegas-Henderson, NV
#12: El Paso-Las Cruces, TX-NM
#13: San Jose-San Francisco-Oakland, CA
#14: New York-Newark, NY-NJ-CT-PA
#15: El Centro, CA
#16: Chicago-Naperville, IL-IN-WI
#16: Dallas-Fort Worth, TX-OK
#18: Fort Collins, CO
#19: San Luis Obispo-Paso Robles, CA
#20: Chico, CA
#21: Reno-Carson City-Fernley, NV
#22: Albuquerque-Santa Fe-Las Vegas, NM
#23: Redding-Red Bluff, CA
#24: Detroit-Warren-Ann Arbor, MI
#25: San Antonio-New Braunfels-Pearsall, TX

WORST CITIES FOR PARTICLE POLLUTION
#1: Bakersfield, CA
#2: Fresno-Madera-Hanford, CA
#2: Visalia, CA
#4: San Jose-San Francisco-Oakland, CA
#5: Los Angeles-Long Beach, CA
#6: Medford-Grants Pass, OR
#7: Fairbanks, AK
#8: Phoenix-Mesa, AZ
#9: Chico, CA
#10: El Centro, CA
#11: Sacramento-Roseville, CA
#12: Cincinnati-Wilmington-Maysville, OH-KY-IN
#13: Indianapolis-Carmel-Muncie, IN
#14: Pittsburgh-New Castle-Weirton, PA-OH-WV
#15: Bend-Prineville, OR
#16: Detroit-Warren-Ann Arbor, MI
#16: Redding-Red Bluff, CA
#18: McAllen-Edinburg, TX
#18: Philadelphia-Reading-Camden, PA-NJ-DE-MD
#18: Eugene-Springfield, OR
#21: Yakima, WA
#22: Chicago-Naperville, IL-IN-WI
#22: Houston-The Woodlands, TX
#24: St. Louis-St. Charles-Farmington, MO-IL
#25: Augusta-Richmond County, GA-SC
#25: Shreveport-Bossier City-Minden, LA

Air Pollution and Health

bookmark_borderClimate Change, Health and Wellness

The real estate you own and live in is greatly impacted by climate change. Pollution that causes global warming impacts your health and well-being. Sea level rise and extreme weather events impact the value of your real estate, insurance and your financial health.

Climate Change and Health

Death By Ozone

Ozone primarily affects the respiratory and immune systems. The damage is permanent, untreatable and often results in death. The Santa Barbara County Air Pollution Control District reports, “Roughly one out of three people in the U.S. is at risk of experiencing ozone-related health effects.”

Health Impacts, Risks, and Adaptation in the United States

Impacts from climate change on extreme weather and climate-related events, air quality, and the transmission of disease through insects and pests, food, and water increasingly threaten the health and well-being of the American people, particularly populations that are already vulnerable.

Pollution Kills Part 2

Pollution will kill you. Usually, it is a slow, painful death.

Air Pollution Kills

Air pollution may be the largest problem facing the world. 600,000 children die per year to indoor and outdoor air pollution.

bookmark_borderFungal Meningitis and Infection Information

In October 2012, an outbreak of fungal meningitis was reported in the United States. The U.S. Centers for Disease Control and Prevention (CDC) traced the outbreak to fungal contamination in three lots of medication used for epidural steroid injections. The medication was packaged and marketed by the New England Compounding Center (NECC), a compounding pharmacy in Framingham, Massachusetts. Doses from these three lots had been distributed to 75 medical facilities in 23 states, and doses had been administered to approximately 14,000 patients after May 21 and before September 24, 2012. Patients began reporting symptoms in late August, but because of the unusual nature of the infection, clinicians did not begin to realize that the cases had a common cause until late September. Infections other than meningitis were also associated with this outbreak, which spanned 19 states. As of March 10, 2013, 48 people had died and 720 were being treated for persistent fungal infections. In November 2012, it was reported that some patients recovering from meningitis were experiencing secondary infections at the injection site.]Although no cases of infection were reported to be associated with any other lots of medication, all lots of all medications distributed by NECC were recalled in separate actions by NECC and regulators. Subsequent analysis identified some contamination in other lots. — Wikipedia

From the state of New Jersey:
NJ Cases Linked to Multi-State Outbreak of Fungal Meningitis & Associated Infections

NJ Case Information as of April 24, 2013

Total Exposures: 705
Total Cases: 51
Meningitis (with or w/o) other infections: 41
Paraspinal/Spinal Infection only: 9
Joint Infection: 1
Deaths: 0